- Tigecycline (Tygacil) is a glycylcycline antibiotic that binds to the 30S ribosomal subunit of susceptible bacteria, inhibiting bacterial protein synthesis.
- However, because of its extensive distribution into tissue, blood levels are low, so tigecycline is probably not a good choice for patients with bacteremia...
- İçindekiler
- Tigecycline nedeniyle ne gibi yan etkiler yaşanabilir?
- Tigecycline kullanmadan önce ne bilinmeli?
- Anahtar sözcükler: glisilsiklin, komplike cilt-yumuak doku infeksiyonları, komplike intraabdominal infeksiyonlar, tigesiklin. SUMMARY. Tigecycline.
- Tigecycline is given IV. It has a large volume of distribution (> 12 L/kg), penetrating well into bone, lung, liver, and kidney tissues.
- Tigecycline A broad-spectrum glyclcycline class of antimicrobial agent that is active against both Gram positive and Gram negative bacteria.
- Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
- Tigecycline is regarded as the first of a new class of glycylcyline antibiotics. Critical comparison to the tetracycline class appears to be lacking in the literature.
- Tigecycline Related Products. SynZeal is a leading innovator in pharmaceutical reference standards. ... Tigecycline-related products are thoroughly characterized.
- An increase in all-cause mortality has been observed in a meta-analysis of Phase 3 and 4 clinical trials in tigecycline-treated patients versus comparator.