- Pharmacodynamics Antibiotic action: Tobramycin is bactericidal; it binds directly to the 30S ribosomal subunit, thereby inhibiting bacterial protein synthesis.
- Tobramycin eye drops are prescribed to treat bacterial eye infections. They work by helping to kill the germs (bacteria) which are causing the infection.
- Each single-use 5 mL ampule contains 300 mg tobramycin, USP and 11.25 mg sodium chloride in sterile water for injection.
- image of a doctor in a lab doing drug, clinical research. Tobramycin Novel Uses: Which Conditions Have a Clinical Trial Featuring Tobramycin?
- Table of contents
- What Drug Tobramycin?
- What is tobramycin for?
- Tobramycin binds irreversibly to one of two aminoglycoside binding sites on the 30S ribosomal subunit, inhibiting bacterial protein synthesis.
- Tobramycin has also been used topically. ... Tobramycin ophthalmic will not treat a viral or fungal infection of the eye.
- Also, I.V. diuretics may increase tobramycin toxicity by altering antibiotic serum and tissue levels. Use drug cautiously in premature infants and neonates.
- Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or intramuscularly.
- Common side effects of tobramycin include upset stomach, pain at the injection site, fever, and headache. Tobramycin can also cause dizziness.