- Sémillon is the main grape in Sauternes and Barsac, sweet white wines from Bordeaux made from late-harvest grapes affected by noble rot.
- For example, Château d’Yquem, perhaps the world’s most coveted sweet wine, is planted roughly to 80% Semillon and 20% Sauvignon Blanc.
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- White Wine Blend. While Semillon used to be one of the top single varietal wines in the world, it is now hard to find one that is made as a single varietal.
- Sémillon was one of the few varietals bought from the south west of France to South Africa by the French Huguenots around the 1690s.
- Semillon üzümü, düşük asitliği ve neredeyse yağlı bir dokusu ile oldukça gövdeli bir şaraptır. Kaliteli Semillon şarapları yıllandırılmaya uygundur.
- Sémillon is widely grown in Australia, particularly in the Hunter Valley north of Sydney, where for a long time it was known as "Hunter River Riesling".
- Semillon produces monovarietal wines but is also used in blends with different grape varieties. A classic blending partner is Sauvignon Blanc.
- Dry white wine produced from Semillon is usually quite rich and relatively low in acidity, so it is often used as a blending grape in dry white Bordeaux.