- Specifically, gentamicin binds to four nucleotides of the 16S rRNA and one amino acid in protein S12.
- With intramuscular use: Gentamicin is used in the doses provided in BNF Publications for the treatment of uncomplicated gonorrhoea, A but these are not licensed.
- Alternatively, 5-7 mg/kg once daily via IV infusion over 30-120 minutes, then adjusted based on serum gentamicin concentrations.
- Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria.
- It is important to tell your doctor/pharmacist if you have any allergies to gentamicin sulfate, aminoglycoside antibiotic like tobramycin, or other drugs.
- Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the...
- Commercially, it is a mixture of the sulfate salts of gentamicin C1, C2, and C1A. It occurs as a white to buff powder that is soluble in water, but insoluble in alcohol.
- Gentamicin is an aminoglycoside antibiotic indicated for the treatment of a variety of bacterial infections. It is normally used as the sulphate salt.
- Gentamicin is also used with other antibiotics to treat infections caused by organisms such as Staphylococcus aureus and certain streptococcal species.