• Tigecycline is a derivative of the tetracycline. Since the drug acts against many different pathogens, it is used as a broad-spectrum antibiotic.
  • Tigecycline is used to treat many different bacterial infections of the skin or the digestive system, as well as pneumonia.
  • - - - S = Susceptible; I = Intermediate; R = Resistant For disk diffusion, use paper disks impregnated with 15 mcg tigecycline.
    • What is tigecycline, and how does it work (mechanism of action)?
    • What are the side effects of tigecycline?
    • What is the dosage for tigecycline?
  • Tigecycline monotherapy was as safe and efficacious as the vancomycin-aztreonam combination in treating patients with cSSSI[6].
  • Tigecycline is regarded as the first of a new class of glycylcyline antibiotics. Critical comparison to the tetracycline class appears to be lacking in the literature.
  • Avoid use of Tigecycline in pediatric patients unless no alternative antibacterial drugs are available. Under these circumstances, the following doses are suggested
  • There is not enough information to tell whether using tigecycline injection increases the risk of death during treatment.
  • Tigecycline is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below